There are four OTC pain medications. It is safe, even helpful, to take some of them together, but not others. A new article in Medical News Today helps sort this out. Although the article speaks only about Aleve and Tylenol it also applies to Tylenol plus the other NSAIDs - aspirin, and ibuprofen.
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For the relief of ankylosing spondylitis, the recommended dosage is 100-125 mg/day, administered as 25 mg q.i.d., with an extra 25-mg dose at bedtime if necessary. Different formulations of diclofenac [Voltaren ® (diclofenac sodium enteric-coated tablets); Voltaren ® -XR (diclofenac sodium extended-release tablets); Cataflam ® (diclofenac

mefloquine. You're more likely to experience coldness, numbness or tingling of the hands and feet if you take ergot derivatives such as ergotamine or methysergide (used to treat migraines) with

The FDA has noted the following ibuprofen warnings and naproxen warnings along with similar risks of other NSAIDs: Heart attack and stroke risk increase even with short-term use, and the risk may begin within a few weeks of starting to take an NSAID. The risk increases with higher doses of NSAIDs taken for longer periods of time.
But the kind you take by mouth, called oral NSAIDs, can cause stomach upset and heart problems. Topical nonsteroidal anti-inflammatory drugs, however, have a lower risk of both. Several topical products (Voltaren Arthritis Pain, Pennsaid, others) are made with a nonsteroidal anti-inflammatory medicine called diclofenac.
low red blood cells (anemia) - pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Common Toradol side effects may include: nausea, stomach pain, indigestion, diarrhea; dizziness, drowsiness; headache; or. swelling. This is not a complete list of side effects and others may occur.
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  • can you take ibuprofen with diclofenac